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The thing is, the company had already submitted its application for approval before these results were released, and that application is based on earlier studies showing strong weight loss and blood sugar improvements on their own

A randomized (159), double-blind, placebo-controlled trial involving 46 adult SLE patients (23 in the synbiotic group, 23 in the placebo group) showed that 60 days of synbiotic supplementation significantly increased butyrate metabolism, reduced the pro-inflammatory cytokine IL-6, and inhibited the elevation of hs-CRP