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Thus, we have developed newer techniques in our research lab which allow us to have patients move their knee sooner to try and decrease the risk of stiffness and the necessity of secondary surgeries to treat their stiffness

A 2025 systematic review in orthopaedic sports medicine noted that most evidence remains preclinical, but the peptide showed promising findings in muscle, tendon, ligament, and bony injury models

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Despite its known effects, the physiological role of DSIP remains unclear, partly due to the lack of identification of its gene and receptor