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In vivo studies Pulmonary toxicity A PMI study on chronic exposure of A/J Mice for 18 months to IQOS smoke showed that IQOS significantly reduced toxicity and carcinogenicity on red blood cell profile, liver function, lung inflammation, emphysematous, and histopathological changes compared to CS in respiratory tract organs 41
Am J Hum Genet 85:493502 Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabon MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM (2016) Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice
Misclassification of Secondhand Smoke Exposure Misclassification may occur when classifying exposures, outcomes, confounding factors, or modifying factors
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