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Golden rule: If a dose is uncomfortable, hold it for another 4 weeks before going up

That standardization lets investigators quantify the repair output total collagen, hydroxyproline as a collagen marker, glycosaminoglycan content, DNA content as a proxy for cell number and compare a treated chamber directly against a control chamber under matched conditions

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Pathophysiological changes in astroglia can be primary or secondary and can result in gain or loss of functions