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First, as adjuncts to standard care, selected strains or formulationssuch as Escherichia coli Nissle 1917, VSL#3, and certain multi-strain probioticsprovide additive or synergistic benefits, improving key outcomes including clinical response, endoscopic remission, and health-related quality of life (HRQoL

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The C max values of each dose were 1.05 0.429, 3.30 0.508, and 26.1 7.82 ng/ml, respectively, and the AUC 0t values were 29.0 2.68, 160 21.0, and 830 247 ng min/mL respectively

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