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In some embodiments, the otic formulation or composition comprises about 0.9% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

To provide better solutions for human health, research is needed to identify which constituents of whole foods (e.g., vitamins, minerals, phytonutrients) are primarily responsible for the synergistic effects seen in the host

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(2022) utilized anthocyanins extracted from black beans to treat type 2 diabetic mice, activating AMPK in skeletal muscle cells to improve glucose utilization and decrease gluconeogenesis, while concurrently down-regulating phosphoenolpyruvate carboxykinase (PEPCK) and glucokinase (GK) activitiescrucial enzymes in glycolysis that boost intracellular glucose catabolism