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Once in the portal circulation, the copper complexes to albumin or amino acids with only a small fraction remaining free. A copper transporter (hCTR) for albumin-bound copper then transports the copper into the hepatocyte.12,13 There it interacts with several proteins that direct the copper to chaperones for incorporation into essential proteins (such as ceruloplasmin, copper/zinc superoxide dismutase, and cytochrome c oxidase), or into lysosomes for biliary excretion

Uses of Hydroxocobalamin Injection Vitamin B12 deficiency Pernicious anemia Megaloblastic anemia Peripheral neuropathy due to B12 deficiency Maintenance therapy in vegans or elderly patients Cyanide poisoning (approved use in emergency medicine) How Does THydroxocobalamin Injection Works Hydroxocobalamin is converted in the body to active coenzyme forms of Vitamin B12, which: Help in red blood cell production Maintain nerve function and myelin sheath Participate in DNA and protein synthesis Act as a cyanide scavenger by binding to cyanide ions and converting them into non-toxic cyanocobalamin , which is excreted in urine Common Side Effects of Hydroxocobalamin Injection Temporary skin redness or itching Mild diarrhea Headache or dizziness Injection site pain or swelling Reddish urine discoloration (harmless) Rare: Hypersensitivity reactions Generally well tolerated

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