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2.3.1 Curcumin Curcumin, the principal polyphenol from Curcuma longa, suppresses PsO-related inflammation by inhibiting IB kinase, thereby preventing NF-B activation and downstream cytokine transcription [40] In murine imiquimod (IMQ) models, curcumin reduces epidermal hyperplasia and attenuates IL-17 and IL-23 signaling

Additionally, neurological symptoms, such as numbness and tingling in the limbs, can manifest due to B12 deficiency

Every experiment was repeated at least three times, and representative data are shown

beyond that, benzyl alcohol's antimicrobial effect diminishes and peptide hydrolysis accelerates