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In mouse models of ASCVD (e.g., LDLR -/- ), a high-fat diet expands bone marrow progenitors and promotes myelopoiesis, accompanied by long-term epigenetic changes linked to NLRP3 inflammasome activation and increased IL-1 secretion

Cigarette smoking is a obvious risk factor for periodontitis, exacerbating oxidative pressure and makes periodontal tissue more susceptible to damage through boosting free radical generation and hindering the activity of the antioxidant enzyme system

Breakouts are spreading to areas where you've never had problems