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ICD-10 Diagnosis Codes for Documentation of Smoking Cessation Services Pharmacotherapy All nonpregnant adults who smoke cigarettes should be offered pharmacotherapy for smoking cessation, especially patients who meet the criteria for nicotine dependence

Nicotine has been shown to increase microvascular blood flow on the brain (animal models), which could increase the permeability of the blood-brain-barrier and subsequently allow toxins to cross this protective field

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Our findings can help inform the FDA as they implement new educational campaigns about cigarette smoke toxins