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Among these symptoms, lipid peroxidation is evident throughout the progression of DN, and the levels of the products of lipid peroxidation, namely, MDA and 8-iso-PGF2 can be indicators to judge or predict the degree of kidney injury in the early stage of DN

It is often referred to as the executioner caspase. Whenever a cell receives signals to undergo a programmed cell death, caspase-3 is the one that gets activated

Alpha Lipoic Acid: ALA is a powerful antioxidant that works with mitochondria, the body's energy powerhouses, to support metabolism, reduce inflammation, assist toxin elimination, and help address oxidative stress associated with aging

They also cause variable degrees of kidney damage