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"The most important thing to take away is that your voice matters." "The most important thing to take away is that your voice matters, because this committee is just issuing a recommendation to the FDA

Primary Ovarian Insufficiency (POI): Also known as premature ovarian failure, this occurs when the ovaries stop functioning normally before the age of 40, leading to a decline in estrogen and irregular or absent periods

Moreover, further endothelial maintenance, mediated by continued VEGF signaling, and additional growth factor interactions (insulin-like growth factor-1 (IGF-1) and platelet-derived growth factor (PDGF)) all promote vascular remodelling and luteal maintenance (77)