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To relax the log(linear) assumption usually applied to continuous doseresponse risk and make the estimates robust to the placement of spline knots, we used an ensemble spline approach to fit the functional form of the doseresponse relationship

"Our findings provide for the first time real world figures for the perceived risk of implantation of lungs from donors with even a heavy smoking history, and they show that such donor lungs may provide a much-needed lease on life to the critically ill patient whose chances of survival diminish with every day or week that passes by on the waiting list

doi: 10.1046/j.1365-2222.1998.00418.x

It plans to expand expeditiously with stores, an Altria spokesperson told CNN Business