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For example, oxidized cysteine (cystine) makes Salmonella enterica more sensitive to gentamicin by disrupting the intracellular redox balance, altered the GSH/GSSG ratio, raised ROS, and increased ferrous iron, which potentially fuels the Fenton reaction, all of which contribute to greater bactericidal activity

Imexon induces an oxidative endoplasmic reticulum stress response in pancreatic cancer cells

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The most common side effects reported in clinical trials include mild nausea, reduced appetite, bloating, and occasional vomiting, particularly during the early weeks of treatment