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Description

To perform virtual screening using pharmacophore model ensembles coupled with YN2, 5 parameters were required: the number of stable and unstable conformations, the minimum ensemble phase score value among known active molecules (, the maximum ensemble phase score value among known active molecules , and the YN2 threshold

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Preclinical models demonstrate reduced apoptosis, diminished fibrotic scar formation, and activation of stem cell pathways[1]

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