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Injectable vitamin B12, which can treat significant deficiencies, may cause the following common side effects: More serious side effects of vitamin B12 injections can include: irregular heartbeat heart palpitations hives or a skin rash Vitamin B12 can cause very rare but serious allergic reactions, or anaphylaxis

Large capacity for medicine Intramuscular injections can deliver large quantities of medicine and deliver a sustained release

After it's released into your system, B12 combines with another molecule called the intrinsic factor that aids its absorption into the small intestine

Vitamin B12 deficiency treatment is often recommended if you experience fatigue, weakness, or nerve-related symptoms