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However, the translation from rodent research to human outcomes is not guaranteed, and no large randomized controlled trials in humans have been published

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Greene CM, Chhabra R, McElvaney NG (2013) Is there a therapeutic role for selenium in alpha-1 antitrypsin deficiency

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The fact that cardiomyocyte iron overload is a storage problem and not an infiltrative process indicates that iron can be removed to reverse cardiac iron overload and associated damage (39)

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